ETHIDIUM

Composition:

Each tablet contains 250 mg of homidium bromide.

Indications:

Ethidium, based on the active ingredient homidium bromide, is indicated for the treatment and subsequent prevention of bovine trypanosomiasis caused by Trypanosoma congolense and Trypanosoma vivax.
A single dose of Ethidium rapidly clears the bloodstream of parasites and, in addition, provides up to six weeks’ protection against further infection. Trials have shown that this period of prophylaxis can be significantly increased in areas of low challenge (until 17 weeks).

Administration & Dosage:

The recommended dosage is 1 mg/kg bodyweight so that one tablet is a standard dose for a 250 kg animal.

Preparation of solution:

Dissolve one tablet in 10 ml water (1 litre per 100 tablets tube). Ethidium K is soluble in cold water, but tablets will dissolve more quickly if first crushed and then stirred into the water, of if hot water is used. To reduce the risk of infection, it is advisable to use sterile or boiled water.

Where the product is required for use over a period of time, it is recommended that a bulk solution be prepared. The use of a bulk solution also simplifies dosing of large numbers of animals and enables accurate dosing by bodyweight. The reconstitued solution of Ethidium will remain stable for 14 days.

The following table gives the volume of solution required for treating by bodyweight.

Weight of animal        Volume of 2.5% w/v 
100 kg                                                 4ml
150 kg                                                 6ml
200 kg                                                8ml
250 kg                                                10ml
300 kg                                                12ml
350 kg                                                14ml
400 kg                                                16ml

Administer the solution by deep intramuscular injection, the preferable site being the middle third of the neck. Massage the site of injection well.

Withdrawal period:

Meat and offals: 30 days – Milk: nil.

Precautions:

Store Ethidium tablets and prepared bulk solution in a safe place. Wash hands after preparation and use of Ethidium.
Long experience with use of Ethidium in the field has shown that there no danger of toxicity when administered as recommended. A slight swelling may occur at the site of injection, but this will quickly disappear.

Keep out of reach of children.
Store in a dry place below 30°C.

Packaging:

Box of 100 tablets.

Category:

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